Synchronous pancreas and liver resection during CRS ± HIPEC. Results of 35 consecutive patients

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Özgül Düzgün
Fatma Kulalı
Ceren Canbey Göret
Gülçiçek Ayrancı
Fikret Ezberci
Ömer Faruk Özkan

Abstract

AIM: To evaluate the results of synchronous pancreas and liver resection in patients with metastatic carcinoma accompanied by peritoneal carcinomatosis (PC) who underwent cytoreductive surgery (CRS)/hyperthermic intraperitoneal chemotherapy (HIPEC).


MATERIAL AND METHODS: Overall, 35 patients with PC who underwent CRS/HIPEC at Umraniye Education and Research Hospital owing to different etiological causes were evaluated for operation procedure, age, sex, comorbid diseases, ASA score, systemic chemo/radiotherapy, duration of surgery, chemotherapy (CT) protocol applied in HIPEC, amount of bleeding, synchronous hepatobiliary resection interventions during operation and short/long-term mortality and morbidity.


RESULTS: Fifteen patients were male and 20 were female. Mean age was 58.375 ± 13.02 (range, 27–85) years.


CRS/HIPEC was performed in 12 patients (34.3%), whereas only CRS was performed in 23 (65.7%) patients. The lowest and highest perioperative bleeding amount was 50 cc and 2000 cc, respectively, and 6 (17.1%) patients had intraoperative bleeding of ≥1000 cc. Synchronous isolated pancreatic resection, hepatic + pancreatic resection and isolated liver resection was performed in 3 (8.6%), 5 (14.3%) and 27 (77.1%) patients treated with CRS/HIPEC. Two patients died within postoperative day 30, and the mortality rate was 5.7%.


CONCLUSION: Hepatopancreatobiliary surgery is a difficult intervention and is associated with serious morbidities.


Synchronisation of hepatopancreatobiliary surgery with CRS/HIPEC may be challenging for the surgeon and clinician.


Here we emphasise that this combination can be performed safely by an experienced team with a multidisciplinary approach and good patient preparation.

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How to Cite
Özgül Düzgün, et al. “Synchronous Pancreas and Liver Resection During CRS ± HIPEC. Results of 35 Consecutive Patients”. Annali Italiani Di Chirurgia, vol. 90, no. 4, July 2019, pp. 297-04, https://annaliitalianidichirurgia.it/index.php/aic/article/view/1322.
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