The clinical outcome of the endoscopic submucosal dissection of colonic polyps larger than 20 mm. A single medical study

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Xiaopeng Wang
Qingqing Meng
Haihong Cui
Jinghua Wang
Rui Qin
Rongjie Jia
Haibin Qiao
Zhenhua Zhang


OBJECTIVE: The aim of this study was to evaluate the safety and efficacy of endoscopic submucosal dissection (ESD) of colonic polyps larger than 20 mm.

MATERIAL AND METHODS: Between March 2017 and July 2019, a gastro-entero endoscopist team resected 24 large colorectal polyps measuring 2035 mm in diameter using the ESD technique. After the injection of a mixture of hydroxypropyl methylcellulose with dilute epinephrine and methylene blue into the submucosal layer, a circumferential incision was performed using an electrosurgical knife.

RESULTS: A total of 24 colorectal polyps (≥20 mm) from 20 patients were evaluated. The mean age of the patients was 60 years; 16 patients were men and 4 patients were women. The mean polyp size removed by colorectal ESD was 35.3 mm (range 20.070.1 mm), and all 24 polyps were larger than 2 cm (100%). There were no cases of delayed bleeding after the colorectal ESD nor were there any post-surgery complications.

CONCLUSION: This study demonstrates the efficacy and safety of carrying out ESD of large polyps. This is important because there is not a large body of literature on this subject in this specific population.

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How to Cite
Wang, Xiaopeng, et al. “The Clinical Outcome of the Endoscopic Submucosal Dissection of Colonic Polyps Larger Than 20 Mm. A Single Medical Study”. Annali Italiani Di Chirurgia, vol. 92, no. 6, Nov. 2021, pp. 660-4,