AIM: The aim of the study was to considerate neoplams of ectopic breast tissue in particular concerning the diagnostic and surgical related problems, analysing our experience in this extremely rare pathology MATERIALS AND METHODS: A group of five women affected by neoplasm ofeectopic breast tissue have been examinated, four of them in axillary breast tissue and the other one in parasternal area. They came to our clinical observation (UOC BCG 21, UOC BCG 27 - Policlinico Umberto I, - Università “Sapienza” di Roma) between 2006 and 2008. All the patient underwent surgical intervention in our department. DiscUSSION: According to the litterature we can assess that this is a rare pathology and so the diagnostic and surgical choices are different from case to case depending on the size, the localization , the local invasion. CONCLUSIONS: This rare pathology can occour in many different forms and areas. This fact makes impossible to create a guideline of diagnosis and treatment. This one must be acted in respect of radicality and when it is possible, of aesthetic criteria.