Emergency liver resection for non-traumatic lesions. A systematic review

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Andra Ciocan
Simona Mărgărit
Adrian Bartoș
Lidia Ciobanu
Ioana Iancu
Razvan A. Ciocan
Nadim Al Hajjar


AIM: Primary liver tumors have an incidence of 20% regarding benign tumors respectively 5.7% of the overall incident cases of cancer. In any major hepatic injury, the surgical treatment has two main goals: hemostasis and excision of the affected liver segments. We aimed to systematic review the non-traumatic emergency liver resections, in order to raise concern about a rather rare, but difficult to treat hepatic pathology, which implies divergent therapeutical approach, and emergency liver surgery remains the first or backup option.

METHODS: A literature survey was performed guided by the words “liver resections”, “major liver resections”, “emergency liver resection”. “hepatocellular carcinoma” using four databases: Pubmed, Scopus, Web of Science and Embase. All titles referred in English, published from 2000 until 2021, were checked for eligibility.

RESULTS: Six publications were considered relevant for major liver resections in emergency, from a total of 331 articles that were reviewed. Large hepatocellular carcinomas and adenomas were the most common types of tumors found at risk for spontaneous rupture. The patients with hemodynamic instability, reduced liver function and large tumors had lower long-term survival and disease-free survival. Major hepatectomy was indicated as a viable solution for prolonging survival rate, whenever the patient’s general status permits it per primam.

CONCLUSIONS: Emergency major liver resection for tumoral causes prolongs survival even if the cause is usually malignant. The tumor can be resected with negative resection margins, respecting the correct oncological requirements, both per primam or staged approach according to each case specifically.

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How to Cite
Ciocan, Andra, et al. “Emergency Liver Resection for Non-Traumatic Lesions. A Systematic Review”. Annali Italiani Di Chirurgia, vol. 94, no. 6, Nov. 2023, pp. 580-6, https://annaliitalianidichirurgia.it/index.php/aic/article/view/3149.
Systematic Review