Treatment Options and the Management of Complications in Hydatid Cysts of the Liver in Endemic Regions

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Yildiray Daduk
Ahmet Seker
Alper Sozutek
Tolga Olmez
Kuntay Kaplan
Huseyin Dur
Gorkem Ozdemir


Background: Hydatid cyst of the liver induced by Echinococcus granulosus is a pervasive zoonotic disease in our region. Its incidence varies across age groups, contingent on community lifespans and hygiene standards. Therapeutic modalities include Puncture, Aspiration, Injection, Re-aspiration (PAIR), and surgery. Due the limited feasability of PAIR, we suggest that surgery represents the optimal treatment in all stages, especially in endemic regions, depending on patient-specific variables.   

Method: Patients with hydatid cyst of the liver treated with PAIR and surgery in our center between January 2016 and January 2022 were analyzed retrospectively. PAIR or cystectomy were applied in treatment. These were then compared in terms of efficacy, feasibility, and complications.   

Results: A single hydatid cyst of the liver was detected in 184 of the 225 cases, two cysts in 33, and three or more cysts in eight. The largest cyst diameter was 233 × 124 mm in the surgery group and 100 × 90 mm in the PAIR group. One hundred thirty-three of the 225 patients underwent open surgery, and no recurrence was encountered in these. However, recurrence was observed 19 patients treated with PAIR. Allergic reaction developed in one case during surgery, postoperative abscess in two cases, biliary fistula in five, and pneumonia in one.   

Conclusion: Surgical treatment should represent the standard procedure since it is safe and effective, ensures complete elimination of the parasite, involves no intraoperative shedding, preserves healthy tissues, and minimizes the risk of long-term recurrence and cavity-related complications.

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How to Cite
Daduk, Yildiray, et al. “Treatment Options and the Management of Complications in Hydatid Cysts of the Liver in Endemic Regions”. Annali Italiani Di Chirurgia, vol. 95, no. 2, Apr. 2024, pp. 213-9, doi:10.62713/aic.3379.