Comparative analysis of hypervascular microcystic serous cystadenoma with MRI and immunohistochemistry

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Burcu Erkan


PURPOSE: Cystic tumors of the pancreas are increasingly common lesions. Unlike mucinous cystic tumors, serous cystadenomas are benign lesions and do not pose a risk of cancer. Often seen in women in the 6th and 8th decades, they are rarely seen in younger women or in male patients. Serous cystadenomas do not require surgical treatment unless they produce symptoms due to compression. Sometimes they may be misdiagnosed as cystic neuroendocrine tumors and resected because of the contrast enhancement on contrast enhanced cross-sectional studies. he purpose of this article is a translational analysis of why a cystic tumor enhances.

MATERIAL AND METHODS: he preoperative T2 HASTE, fat-suppressed T2 Turbo Spin Echo sequences, magnetic resonance cholangiopancreatography, difusion weighted images, ex-vivo high-resolution T2 HASTE images of the post-operative pathologic specimen and immunohistochemical analysis with vascular marker CD31 were compared in a 58-yearold male patient with a pancreatic corpus microcystic serous cystadenoma.

RESULTS: he nodular lesion is observed as luid signal in T2 weighted sequences and enhancing in postcontrast series. Exvivo high-resolution MRI has also revealed cysts with millimetric diferent sizes and septations within the lesion. Evaluation with the CD31 vascular marker showed that ibrous septa between the cysts were dense vascular and stained.

CONCLUSION: We show here that microcystic serous cystadenomas have intense vascularity of their septations that enhance in cross-sectional studies, especially when the cyst diameter is smaller.

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How to Cite
Erkan, Burcu. “Comparative Analysis of Hypervascular Microcystic Serous Cystadenoma With MRI and Immunohistochemistry”. Annali Italiani Di Chirurgia, vol. 8, no. October, Oct. 2019, pp. 1-5,
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