Predictive factors for incidental gallbladder cancer (IGBC) in patients undergoing cholecystectomy for presumed benign disease.

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Published: Mar 1, 2018

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Annunziata Panebianco
General Surgery Unit, “V. Bonomo” Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
Rita Laforgia, Annalisa Volpi,
General Surgery Unit, “V. Bonomo” Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
Rossana Mancarella
Institute of Demography, Faculty of Political Sciences, University of Bari, Italy
Giuseppe Carbotta
General Surgery Unit, “V. Bonomo” Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
Clelia Punzo,
General Surgery Unit, “V. Bonomo” Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
Concetta Lozito
General Surgery Unit, “V. Bonomo” Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
Rosaria Tucci
General Surgery Unit, “V. Bonomo” Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
Marina Minafra,
General Surgery Unit, “V. Bonomo” Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
Antonella Delvecchio
General Surgery Unit, “V. Bonomo” Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
Salvatore Fedele
General Surgery Unit, “V. Bonomo” Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
Paolo Ialongo
General Surgery Unit, “V. Bonomo” Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
Anna Paterno
Institute of Demography, Faculty of Political Sciences, University of Bari, Italy
Nicola Palasciano
General Surgery Unit, “V. Bonomo” Emergency and Organ Transplantation Department, University of Bari, Bari, Italy

Abstract

AIM: The incidence of incidental gallbladder cancer (IGBC) is estimated at 0.3-2.1%. The purpose of our study is to evaluate IGBC incidence in our department and to establish its predictive factors, considering patients’ clinical characteristics and pre-operative ultrasound gallbladder features.


MATERIAL OF STUDY: From January 2012 to December 2015, 434 patients (225 females and 209 males) were enrolled in this retrospective observational study in our General Surgery Department. To analyze potential predictive factors, we divided all the patients into two groups: patients with and without histological diagnosis of IGBC. We focused our attention on the patients’ clinical characteristics and preoperative ultrasound gallbladder measurements RESULTS: Seven cases were post-operatively identified as incidental gallbladder cancer (IGBC) and after histological examination an IGBC incidence of 1.6% was encountered.


DISCUSSION: Considering the increasing numbers of video laparoscopic cholecystectomies (VLC) performed worldwide, cases of IGBC are appearing more frequently. In most cases of IGBC, a second surgical look will be necessary because of feasibility and safety procedures.


CONCLUSIONS: There is no possibility to establish which risk factors might be predictive for IGBC because of a discordance in the literature and a statistical analysis with low sample size. An accurate surgical procedure needs to be performed to reduce the spread of neoplastic cells and, as a result, improve long-term outcomes.

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How to Cite
Annunziata Panebianco, et al. “Predictive Factors for Incidental Gallbladder Cancer (IGBC) in Patients Undergoing Cholecystectomy for Presumed Benign Disease. ”. Annali Italiani Di Chirurgia, vol. 89, no. 2, Mar. 2018, pp. 118-27, https://annaliitalianidichirurgia.it/index.php/aic/article/view/1005.
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Vol. 89 No. 2 (2018)
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