Red cell distribution width and mean platelet volume as predictors of anastomotic dehiscence in colorectal surgery

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Published: Sep 1, 2018
Keywords:
Anastomotic Dehiscence, MPV, RDW

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Panagiotis Paliogiannis
Departement of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy
Federico Attene
Departement of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy
Alberto Porcu
Departement of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy
Maria Laura Cossu
Departement of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy
Alessandro Fancellu
Departement of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy
Antonio Mario Scanu
Departement of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy
Giorgio Carlo Ginesu
Departement of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy
Giuseppe Cherchi
Departement of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy
Pietro Niolu
Santissima Annunziata” Hospital of Sassari (AOU), Sassari, Italy.
Massimiliano Coppola
“Nostra Signora della Mercede” Hospital of Lanusei, Lanusei, Italy
Ciriaco Carru
Department of Biomedical Sciences, University of Sassari, Sassari, Italy
Angelo Zinellu
Department of Biomedical Sciences, University of Sassari, Sassari, Italy

Abstract





AIM: One of the most serious complications in modern colorectal surgery is the occurrence of an anastomotic dehiscence. The aim of this study was to evaluate the role of preoperative red cell distribution width (RDW) and mean platelet volume (MPV) as predictors of anastomotic dehiscence in elective surgery for colorectal cancer.


MATERIALS AND METHODS: Forty-two patients with a clinically manifested anastomotic dehiscence after oncological col- orectal surgery, and 42 controls matched for age, sex, pathological stage and tumor localization were enrolled. Correlations between the preoperative RDW and MPV values and anastomotic dehiscence were investigated.


RESULTS: Both the median RDW value (14.4 % vs 13.1%; p=0.007) and the median MPV value (8.0 fL vs 7.5 fL; p=0.037) were significantly higher in patients with anastomotic dehiscence than in those without. In multiple regression analysis only the RDW remained significantly associated with anastomotic dehiscence.


CONCLUSIONS: The preoperative values of RDW may be useful in predicting anastomotic damage in elective oncological surgery.





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How to Cite
Panagiotis Paliogiannis, et al. “Red Cell Distribution Width and Mean Platelet Volume As Predictors of Anastomotic Dehiscence in Colorectal Surgery”. Annali Italiani Di Chirurgia, vol. 89, no. 5, Sept. 2018, pp. 419-24, https://annaliitalianidichirurgia.it/index.php/aic/article/view/1137.
Issue
Vol. 89 No. 5 (2018)
Section
Case Report