Long-term results of conversion surgery for advanced gastric cancer

Abstract

AIM: Upon this topic, randomized trials regarding gastrectomized and combination therapy with gastrectomy and chemotherapy have been made and survival has been prolonged to 15 months. In this study, we aimed to present our results by retrospectively classifying them according to Yoshida classification in stage 4 gastric cancer patients who have been operated in the last 5 years.

METHODS: The datas of 102 cases were collected prospectively and analyzed retrospectively between years 2016 and 2021. All cases were classified according to Yoshida classification.

RESULTS: 22 (21,5%) cases in category 1, 35 (34,3%) cases in category 2, 30 (29,4%) cases in category 3 and 15 (14,7%) cases in category 4. Overall survival rate of 1,3 and 5 year period in category 1 patients were 90%, 50% and 25% respectively. Mean survival time was 24 months. In category 2, overall survival rate of 1,3 and 5 years was 90%, 50% and 25% respectively. Mean survival time was 18 months. In category 3, overall survival rate of 1,3 and 5 years was 50%, 10% and 0% respectively. Mean survival time was 12 months. Lastly, in category 4, overall survival rate of 1,3 and 5 years was 40%, 0% ve 0% respectively and mean survival time was 9 months.

CONCLUSION: We found that gastric cancer tumors without peritoneal involvement and responding to effective chemotherapy had longer survival and disease-free survival after conversion surgery.