Franco Bassetto
Plastic and Reconstructive Surgery Unit, Department of Neurosciences, University of Padova, Padua, Italy
Giorgio Pajardi
Department of Clinical Sciences and Community Health, The University of Milan, Milan, Italy
Bruno Battiston
Department of Orthopedics and Traumatology, Orthopedic and Trauma Center, AOU Città della Salute e della Scienza, Turin, Italy
Massimo Corain
Department of Hand Surgery and Microsurgery, University Hospital of Verona, Verona, Italy
Silvia Sargenti
Department of Hand Surgery and Microsurgery, University Hospital of Verona, Verona, Italy
Carlotta Scarpa
Plastic and Reconstructive Surgery Unit, Department of Neurosciences, University of Padova, Padua, Italy
Chiara Novelli
Department of Clinical Sciences and Community Health, The University of Milan, Milan, Italy
Cesare Tiengo
Plastic and Reconstructive Surgery Unit, Department of Neurosciences, University of Padova, Padua, Italy
Andrea Vitali
Hand Surgery Unit, Palagi Hospital (I.O.T.), Azienda Usl Toscana Centro, Florence, Italy
Federico Facchin
Plastic Surgery Unit, Azienda ULSS 8 Berica, San Bortolo Hospital, Vicenza, Italy;Plastic and Reconstructive Surgery Unit, Department of Neurosciences, University of Padova, Padua, Italy
Maddalena Bertolini
Department of Orthopedics and Traumatology, Orthopedic and Trauma Center, AOU Città della Salute e della Scienza, Turin, Italy
Luciano Cara
Orthopedics and Reconstructive Microsurgery Unit, Cagliari, Italy
Giancarlo Caruso
Hand Surgery Unit, Palagi Hospital (I.O.T.), Azienda Usl Toscana Centro, Florence, Italy
Abstract
AIM: Dynavisc® is a novel surgical product made of carboxymethylcellulose (CMC) and Polyethylene Oxide (PEO) designed to reduce post-surgical adhesions in tendons surgery. A multicenter retrospective cohort study was performed to investigate the clinical safety and efficacy of the Dynavisc® gel in reducing post-surgical adhesions after flexor tenolysis in zone 2.
MATERIAL OF STUDY: Thirty-one patients suffering from stiff finger after flexor tendon repairs in zone 2 treated with standard release with (18 Dynavisc®-treated group) or without (13 controls) anti-adhesion gel application into the flexor tendon sheath and around the site of the tenolysis, were collected in five different hand surgery units. Safety profile and functional outcomes (based on TAM test and the The Quick-DASH questionnaire) were examined from patients’ charts and analyzed.
RESULTS: The application of Dynavisc® posed no safety concerns and it was not related to any additional complication.
CONCLUSIONS:This clinical study confirm the safety of Dynavisc® gel application in hand surgery demonstrating its poten-tial long-term benefits after flexor tendon tenolysis.