Alessandra Di Sibio
Department of Radiology, S. Salvatore Hospital, L’Aquila, Italy
Marco Varrassi
Specialist of Anesthesiology and Reanimation, Gülhane Training and Research Hospital, Department of Anesthesiology and Reanimation, Ankara, Turkey
Olga Venditti
Medical Oncology Unit,” St. Salvatore” Hospital, L’Aquila, Italy
Ernesto Di Cesare
Department of Applied Clinical Science and Biotechnology, University of L’Aquila, L’Aquila, Italy
Lucia Romano
Department of Applied Clinical Science and Biotechnology, University of L’Aquila, L’Aquila, Italy
Antonio Giuliani
Department of Applied Clinical Science and Biotechnology, University of L’Aquila, L’Aquila, Italy
Maria Carmela De Donato
Department of Radiology, S. Salvatore Hospital, L’Aquila, Italy
Francesco Carlei
Department of Applied Clinical Science and Biotechnology, University of L’Aquila, L’Aquila, Italy
Alessandro Parisi
Medical Oncology Unit, “St. Salvatore” Hospital, Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
Mario Schietroma
Department of Applied Clinical Science and Biotechnology, University of L’Aquila, L’Aquila, Italy
Michele Latessa
Department of Radiology, S. Salvatore Hospital, L’Aquila, Italy
Riccardo Monti
Department of Radiology, S. Salvatore Hospital, L’Aquila, Italy
Corrado Ficorella
Medical Oncology Unit, “St. Salvatore” Hospital, Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
Abstract
Chemotherapy is associated with different patterns of histopathological changes of the non-tumor-bearing liver. Hepatic
infarction represents a relatively rare condition; the prevalence in several series of consecutive autopsies is 1.1%. To the
best of our knowledge, no cases of liver infarction secondary to chemotherapy have been reported to date. We report a
case of segmental hepatic infarction following the adjuvant chemotherapy with Oxaliplatin and Capecitabine in a patient
who had undergone total gastrectomy and distal esophagectomy for gastric cancer. Liver infarction is usually managed
by conservative therapy; interventional procedures such as percutaneous imaging-guided drainage or surgical evacuation
should be reserved in cases where septic complications occur, with development of a hepatic abscess from the necrotic
area. It is important to avoid misdiagnoses with liver metastases in order to define the most appropriate clinical management strategy